Diffusion Imaging Journal Club
Since many people have expressed interest in Diffusion Imaging lately, I’ve decided to promote a journal club so we together can understand more about this emerging MRI modality. The Diffusion Imaging Journal Club (DIJC) will attempt to encompass several aspects of diffusion imaging, including acquisition, signal representation, quantification, visualization, tractography, registration (spatial and temporal normalization) and several applications (human brain, heart, etc). We will meet once a week (see schedule below) for about 1 hour to discuss several papers in the field. At each meeting, we discuss one or two papers at a time (depending on length). I would encourage those interested to select one or two papers of their choice to make a short talk (~20min), as means to start our discussion.	Our meetings take place at 1PM (unless indicated otherwise in the schedule below) at the: Diagnostic Radiology Conference Room 333 Brady Memorial Laboratory The purpose of this journal club is to understand what goes on in the field, to spark new ideas and to foster new collaborations. If you are interested in participating, contact me for further information. Marcel Jackowski e-mail: mjack@noodle.med.yale.edu

General reading

· D. Le Bihan, J. F. Mangin, C. Poupon, et al. "Diffusion Tensor Imaging: Concepts and Applications", Journal of Magnetic Resonance Imaging, v.13, 2001.

· D. Le Bihan and P. Van Zijl, "From the diffusion coefficient to the diffusion tensor", NMR in Biomedicine, v. 15, 2002.

· P. Basser, D. Jones, "Diffusion-tensor MRI: theory, experimental design and data analysis - a technical review", NMR in Biomedicine, v. 15, 2002.

· W. S. Price, "Pulsed-Field Gradient Nuclear Magnetic Resonance as a Tool for Studying Translational Diffusion: Part 1. Basic Theory", Concepts in Magnetic Resonance, v. 9:5, 1997.

· W. S. Price, "Pulsed-Field Gradient Nuclear Magnetic Resonance as a Tool for Studying Translational Diffusion: Part 2. Experimental Aspects", Concepts in Magnetic Resonance, v. 10:4, 1998.

· J. J. Neil, “Measurement of Water Motion (Apparent Diffusion) in Biological Systems”, Concepts in Magnetic Resonance, v. 9(6), 1997.

· D. Tuch, “Diffusion MRI of Complex Tissue Structure”, Ph.D. Thesis, MIT, 2002.

· P. J. Basser, J. Matiello and D. LeBihan, “Estimation of the Effective Self-Diffusion from NMR Spin Echo”, Journal of Magnetic Resonance, Series B, 103, 1994.

· P. J. Basser and C. Pierpaoli, “Microstructural and Physiological Features of Tissues Elucidated by Quantitative-Diffusion-Tensor MRI”, Journal of Magnetic Resonance, Series B, 111, 1996.

Schedule

September 23	Introduction to Diffusion Imaging (slides) Marcel Jackowski
September 30	No meeting – MICCAI'04 conference
October 7	The diffusion MRI pulse sequence (slides) Maolin Qiu Diffusion MRI using a Twice-Refocused Spin Echo
October 14	Source of anisotropy in neural tissue Marcel Jackowski The Basis of Anisotropic Water Diffusion in the Nervous System - A Technical Review Magnetic Resonance Microimaging of Intraaxial Water Diffusion in Live Excised Lamprey Spinal Cord
October 21,28	Definition, Measurement and Visualization of Diffusion Tensors Hemant Tagare Theoretical Analysis of the Effects of Noise on Diffusion Tensor Imaging Visualizing diffusion tensor MR images using Streamtubes and Streamsurfaces
November 4	Brain Tumor Diagnosis by Diffusion Tensor Imaging Yuenan Wang Peritumoral Diffusion Tensor Imaging of High-Grade Gliomas and Metastatic Brain Tumors
November 11	Group Discussion An error analysis of white matter tractography methods: synthetic diffusion tensor fields simulations
November 18	White Matter and Biology of Neuroscience Robert Fulbright
November 25	No meeting – Thanksgiving
December 9	Group Discussion Al Sinusas Computational Cardiac Anatomy using MRI
December 16	Group Discussion Lawrence Staib Validation of Diffusion Tensor Magnetic Resonance Axonal Fiber Imaging with Registered Managnese-Enhanced Optic Tracts
TBA	Parallel Diffusion Imaging Techniques Alexander Pine

Last modified: 12/14/2004.