Nonlinear Estimation and Modeling of fMRI Data using
Spatio-Temporal Support Vector Regression



Yongmei Michelle Wang, Robert T. Schultz, T. Todd Constable and Lawrence H. Staib

Yale University

Information Processing in Medical Imaging, July 2003



(a) (b) (c) (d)

Fig. 2. Simulated 2D + T data. Top row: time T vs. spatial axis X; Bottom: spatial axis Y vs. X.
(a): Ground truth data; (b): Simulated noisy data with noise level N(0, 30*30); (c): Restored data by our SVR (W-model = 1); (d): Gaussin smoothed data with s.t.d. = 0.5.




Fig. 3. Effects on time course with varying W-scale and W-model in our SVR. (Simulated noise level: N(0, 30*30).)




Fig. 4. ROC curves for simulated noisy 2D + T data. (Average effect of three noise levels.)



(a): by SVR (t > 7.8); (b): by t-test (t > 4.2); (c): by t-test (t > 2.3).

Fig. 5. Results comparison for real fMRI data from a visuospatial task.




Fig. 6. Time courses of an activated voxel for the real fMRI data in Fig. 5.


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